Postdoc
eruzzo@ucla.edu
Gonda 2309
Educational Background:
PhD: Genetics and Genomics, Duke University (Durham, NC)
BS: Cell and Molecular Biology, University of Washington (Seattle, WA)
Research Project:
My research in the Geschwind lab focuses on understanding the genetic etiology of autism spectrum disorder (ASD). Recently, a number of large-scale exome sequencing projects (primarily focusing on de novo mutations in simplex ASD families) have confidently identified ~70 ASD-risk genes; however, evidence suggests that hundreds of novel ASD-risk genes remain unidentified. As part of the Hartwell Autism Research and Technology Initiative (iHART), we have generated high coverage (30X) whole-genome sequence (WGS) data for >4,000 individuals from the family-based Autism Genetic Resource Exchange (AGRE) cohort. These WGS data enable us to explore the role of non-coding variants by functionally annotating known regulatory regions as defined in developing human brain. Additionally, given that the majority of participating families have multiple affected individuals, our research focuses on exploring the role of inherited variation in conferring ASD risk.
Joined the lab:
2014
